Linking RNA structure and function Date: September 8, 2016 Source: Massachusetts Institute of Technology Summary: Several years ago, biologists discovered a new type of genetic material known as ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

To study—and potentially modify—the functions of non-coding RNAs, we need to determine their structure. Scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) and the Hebrew ...

Biologists have deciphered a lncRNA structure and used the information to investigate its cellular protein interactions.

The functions of biomolecules, including lipids, nucleic acids and especially proteins are determined to a great extent by their structure. This structure–function relationship is a foundation ...

Scientists determine structure of key factor in RNA quality control Date: June 9, 2022 Source: Memorial Sloan Kettering Cancer Center Summary: In biology, getting rid of stuff can be just as ...

The list goes on and on. The breadth of functions that RNA performs explains why defective RNA degradation pathways can have such cascading disease-causing effects.

Inosine is a key nucleoside in RNA that contributes to tRNA function, A-to-I editing, and gene regulation, with applications in biotechnology and therapeutics.

Implications of RNA Structure on Function They also examined the extent of conservation, and found about 24% of the single-stranded to be highly conserved, with over 80% conserved in SARS-CoV, and ...

The RNA exosome degrades RNA that is faulty, harmful, or no longer needed. Scientists have used cryo-EM microscopy to determine the structure of a key part of the degradation machinery, called NEXT.