Oct 27, 2017 · pKa is an acid dissociation constant used to describe the acidity of a particular molecule. Its value is directly related to the structure of the given compound.

Jun 18, 2010 · Based on experiment (i.e. measuring pKa), pi-donation wins out as being more important. What that means is that the resonance form where oxygen donates a lone pair to …

Approximate pKa chart of the functional groups: values to know 1. Protonated carbonyl pKa = ‐7 Other important pKa’s 2. Protonated alcohol or ether pKa = ‐2 to ‐3 H2 = 35 3.

Oct 31, 2014 · Yes, it is the other way around. Ketones (pKa ~ 20) are more acidic than esters (pKa ~ 25). The figure below shows the resonance structures for the enolate anion, a …

pKa Data Compiled by R. Williams pKa Values INDEX Inorganic 2 Phenazine 24 Phosphates 3 Pyridine 25 Carboxylic acids 4, 8 Pyrazine 26 Aliphatic 4, 8 Aromatic 7, 8 Quinoline 27 …

While the pK a values for alkyl C-H bonds is typically on the order of 40-50, pK a values for these alpha hydrogens is more on the order of 19-20. This can most easily be explained by …

Let's compare pK a of the common systems: aldehyde pK a = 17, ketone pK a = 19 and an ester pK a = 25, and try to justify the trend. The difference between the 3 systems is in the nature of …

esters (enolates) 18-21 25 hydrogen cyanide 9.1 tertiary alcohols phenols 10 1,3-diketones 9 10.5 10.6 15.7 protonated amines water cyclopentadiene amides (aromatic) 15 15 conjugate acid …

pKa list for alpha-hydrogens of carboxylic acids, nitro compounds, amides, aldehydes, ketones, esters, nitriles, amides and alkanes. Note - the pKa value is for the hydrogen highlighted in red …

ESTERS KETONES n [30.2 (THF)] pKa's of CH bonds in Hydrocarbons and Carbonyl Compounds Me Me Me Me Me O X O Et Et S i-Pr i-Pr O O t-Bu Me Ph X Ph i-Pr O O LiO O …