What Happens If Your Cilia are Damaged? If, whether through hereditary or external factors, your cilia become damaged, your lungs will struggle to clear mucus independently. Imagine if those …

Feb 4, 2022 · Primary ciliary dyskinesia (PCD) affects your respiratory system and is a rare disorder. It’s due to issues with cilia, microscopic hair-like organs. Healthy cilia use wave-like …

In this review we summarize current knowledge regarding airway ciliated cells and cilia, how they function to maintain a healthy epithelium, and how disorders of cilia structure and function …

Primary ciliary dyskinesia (PCD) is a heterogeneous, predominantly autosomal recessive genetic disease that is the result of impaired ciliary function and defective mucociliary clearance in the …

Jan 1, 2008 · This article provides evidence that IFT is essential for primary cilia assembly and function in mammals and that defects in cilia assembly can lead to polycystic kidney disease.

Nov 22, 2022 · In primary ciliary dysfunction, mutations in genes encoding for axonemal structures of motile cilia result in cilia that are abnormal in structure and function. Defects can …

Jun 7, 2024 · Primary ciliary dyskinesia is caused by genetic mutations that affect the tiny hairline cilia in the lungs, nose and ears, impairing their ability to remove germs and pollutants, and …

Jul 3, 2019 · Like tiny brooms, cilia sweep mucus, bacteria, and dust particles from your lungs and airways toward your throat and out of your body. These tiny sweepers are vital for keeping you …

The prototypical disorder of respiratory cilia is primary ciliary dyskinesia, an inherited disorder that leads to impaired mucociliary clearance, to repeated chest infections, and to the progressive …

Following infection of the respiratory tract, coronaviruses exploit the cilia to invade and replicate in epithelial cells while also damaging the cilia to facilitate the spread and exacerbation of …