miRNAs - Latest research and news | Nature
WEBOct 1, 2024 · miRNAs articles from across Nature Portfolio. micro RNAs (miRNAs) are a type of non-coding RNA (ncRNA), ~21 24 nucleotides in length, that function in the post-transcriptional regulation of gene ...
microRNAs in action: biogenesis, function and regulation
WEBJun 28, 2023 · In this Review, the authors describe how the application of new technologies to the microRNA (miRNA) field has yielded key insights into miRNA biology.
MicroRNA amplification and detection technologies: opportunities …
WEBDec 12, 2018 · Food and Drug Administration (FDA) has already approved a handful of miRNA-based tests aimed at guiding therapeutic management. For instance, for the classification of cancer of unknown primary ...
MicroRNA therapeutics: towards a new era for the management of …
WEBFeb 17, 2017 · Overview of microRNA (miRNA) biogenesis, highlighting key mutations and deregulated factors that play a part in diseases related to alterations in miRNAs. miRNAs are produced in a tightly ...
MicroRNA profiling: approaches and considerations - Nature
WEBApr 18, 2012 · Owing to the important role of microRNAs in gene regulation, profiling repertoires of expressed microRNAs can be informative in basic research and clinical settings. This Review describes the ...
miRNA in immune cells - Latest research and news | Nature
WEBSep 6, 2024 · MicroRNAs (miRNAs) are small, ribonucleic acid (RNA) molecules that regulate gene expression by binding to specific messenger RNAs (mRNAs). In immune cells, miRNAs have been reported to regulate ...
MicroRNA: trends in clinical trials of cancer diagnosis and therapy ...
WEBJul 10, 2023 · Signal Transduction and Targeted Therapy (2024) As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in cancer development. Since the discovery of the identity and ...
Regulation of microRNA function in animals - Nature
WEBAug 14, 2018 · Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as key regulators of biological processes in animals. These small RNAs form complex networks that regulate cell ...
Regulation of microRNA biogenesis - Nature Reviews Molecular …
WEBJul 16, 2014 · MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA silencing. Biogenesis of miRNA is under tight temporal and spatial control. Dysregulation of miRNA is ...
Diversifying microRNA sequence and function - Nature
WEBJun 26, 2013 · Various mechanisms have now been identified that regulate miRNA stability and that diversify miRNA sequences to create distinct isoforms. The production of different isoforms of individual miRNAs ...