The Mucorales is the largest and best-studied order of zygomycete fungi. Members of this order are sometimes called pin molds . The term mucormycosis is now preferred for infections caused by molds belonging to the order Mucorales.

Mucorales is a complex fungal group, including eleven different genera that can infect humans. This heterogeneity is associated with species-specific invasion pathways and responses to the host defense mechanisms.

Mucorales are thermotolerant moulds that are supposedly ubiquitous in nature and widely found on organic substrates, including bread, decaying fruits, vegetable matter, crop debris, soil between growing seasons, compost piles, and animal excreta.

Mucorales produce their uni-celled asexual spores (sporangiospores) endogenously, i.e., inside specialized cells. In contrast to the formation of conidia, cell walls of the sporangiospores are formed without the involvement of pre-existing cell walls.

Mucorales are significant fungal pathogens associated with high mortality, innate resistance to voriconazole, and variable susceptibility to the remaining mould-active triazoles.

Jun 13, 2010 · Mucorales Overview. The Mucorales, or its vernacular equivalent, began as a modest order of four families (van Tieghem, 1878) and gradually the number of families has increased as new taxa have been described.

Jun 27, 2024 · Mucormycosis is a life-threatening spectrum of invasive fungal disease (IFD) caused by genera of the order Mucorales. 1 Previously known as zygomycosis because infections were caused by fungi of the former phylum, Zygomycota.

Nov 14, 2019 · The order Mucorales has now been assigned to the phylum Mucoromycota and is comprised of 261 species in 55 genera. Of these accepted species, 38 have been reported to cause infections in humans, as a clinical entity known as mucormycosis.

Mucormycosis is an uncommon, yet deadly invasive fungal infection caused by the Mucorales moulds. These pathogens are a WHO-assigned high-priority pathogen group, as mucormycosis incidence is increasing, and there is unacceptably high mortality with current antifungal therapies.

Mucorales are filamentous fungi that produce sporangiospores (asexual spores) contained within a saclike structure called a sporangium. From: Kendig's Disorders of the Respiratory Tract in Children (Ninth Edition) , 2019