Mar 17, 2023 · The ciliary body contains muscles that make your lens change its shape while you’re focusing on what you’re seeing. When you’re looking at something closer, your lens becomes rounded. When you’re looking at something farther away, your lens flattens out.

Feb 4, 2022 · Primary ciliary dyskinesia (PCD) is a rare, inherited disorder. It affects cilia, tiny hair-like organs that help your body clear mucus. PCD leads to recurring, often severe respiratory infections.

Primary ciliary dyskinesia (PCD) is a rare inherited disorder caused by defects in the structure and/or function of cilia. Cilia are tiny hair-like structures, which are required to move fluids and particles in various parts of the body, including the airways.

Primary ciliary dyskinesia (PCD) is an inherited disorder which affects the movement of tiny hair-like structures on body cells, known as cilia. Cilia are present on many types of cells, and particularly on those in the respiratory tract. In PCD, the cilia are …

Nov 22, 2022 · Primary ciliary dysfunction (PCD), first described in 1976, is a disorder of the structure and function of motile cilia that results in chronic oto-sinopulmonary disease.[1] Cilia are hair-like structures that exist on the surface of cells.[2]

Sep 17, 2020 · Our understanding of the genetics, pathophysiology, and clinical manifestations of motile ciliopathies, including primary ciliary dyskinesia (PCD), has rapidly advanced since the disease was linked to ciliary ultrastructural defects nearly 5 decades ago.

Ciliopathies comprise a group of disorders associated with genetic mutations encoding defective proteins, which result in either abnormal formation or function of cilia.

Ciliopathies encompass a broad spectrum of diseases stemming from dysfunction of the primary (non-motile) cilia, present on almost all cells in the human body. These disorders include autosomal dominant and recessive polycystic kidney diseases, nephronophthisis, and multisystem ciliopathies such as …

Nov 25, 2014 · In recent decades, cilia have moved from relative obscurity to a position of importance for understanding multiple complex human diseases. Now termed the ciliopathies, these diseases inflict devastating effects on millions of people worldwide.

Understanding Primary Ciliary Dyskinesia and Other Ciliopathies. Horani A, Ferkol TWJ Pediatr 2021 Mar;230:15-22.e1.