Contour Airlines begins air service from Cape Girardeau Regional Airport to Chicago O'Hare International Airport on Tuesday, Oct. 1.

Dockworkers at ports from Maine to Texas have started walking picket lines in a strike over wages and automation that could reignite inflation and cause shortages of goods if it goes on more than a ...

A ribbon-cutting ceremony and tour will celebrate the new airport terminal at the Cape Girardeau Regional Airport on Tuesday, ...

RIPLEY COUNTY, Mo. (KFVS) - A Naylor, Missouri woman was seriously injured in a single-vehicle crash on Monday, September 30.

Christa Weber, executive director at Discovery Playhouse, shows us how to make pumpkin pie playdough, a kid-friendly activity ...

SCOTT CITY, Mo. (KFVS) - Multiple crews are on the scene of a house fire in Scott City on Tuesday morning, October 1.

Iran is preparing to “imminently” launch a ballistic missile attack on Israel, according to a senior U.S. administration official, who warned Tuesday of “severe consequences” should it take place.

We’re on Week 6 of Heartland Football Friday Top 12 Plays. Take a look at some of the best plays we saw this past Friday.

SIU Public Health is working with the Carbondale Community High School Key Club and SIU Eta Sigma Gamma to host the ninth ...

There are 448 “missing person” cases in the state of Missouri right now, and nearly 25,000 nationwide, according to the ...

Union County Sheriff David Wilkins said there have been a number of reports of stolen political signs coming into his department this election season.

Law enforcement is searching for a Paducah man who is wanted in connection with a drug trafficking investigation.