This bispecific T-cell engager targeting DLL3 was considered very promising because notch signaling is a regulator of neuroendocrine differentiation in SCLC ... stage-small-cell-lung-cancer 8. Peters ...

Topics include: the definition of derivative (algebra and geometry), differentiation skills for polynomials, logs, exponentials and trig functions, the Chain Rule and differential approximations. From ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions characterised by inflammation of the intestinal tract. Alterations in ...

Threatening the global community is a wide variety of potential threats, most notably invasive pest species. Invasive pest species are non-native organisms that humans have either accidentally or ...

Regulatory T cells (Tregs) specifically expressing Forkhead box P3 (Foxp3) play roles in suppressing the immune response and maintaining immune homeostasis. After maturation in the thymus, Tregs leave ...

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