Modifications in proteins after they are synthesized (post-translational) are changes that play a fundamental role in cell ...

Researchers at Vanderbilt University have found that boosting a signaling pathway in the brain can prolong ketamine’s antidepressant effects, at least in mice.

-- PAS-004 shows up to 91% inhibition of pERK, confirming substantial target engagement -- -- One patient in cohort 4A with stage 4 KRAS G12R mutated pancreatic cancer achieves over 5 months of ...

Activating RAF1 alterations include fusions, amplifications, and point mutations. 13 Alterations that increase RAF1 activity promote tumorigenesis through hyperactivation of the MAPK pathway. 14 ...

Healthletic’s Ultimate Methylene Blue Sets New Standard in Cognitive and Mitochondrial Support with 99.9% USP-Grade Purity, Third-Party Lab Verification, and Transparent Sourcing.New York, May ...

Using an algorithm they call the Krakencoder, researchers at Weill Cornell Medicine are a step closer to unraveling how the brain's wiring supports the way we think and act. The study, published June ...

Reishi mushrooms are popular in Eastern medicine and may have various health benefits. Learn more about the possible benefits, side effects, and dosage recommendations.

The model structure accounted for: (i) pre-existing phenotype differences in pathway activity among patient tumors and (ii) tumor-specific phenotypic response to therapy. Resistant cancer phenotypes, ...