Individuals with chronic neurological disorders including motor neuron disease (MND), chronic inflammatory ... impact of lockdowns on individuals with MND and other chronic neuromuscular disorders ...

SMA is a progressive condition that affects motor neurons, the specialized cells that control voluntary muscle movement. It has five subtypes, of which type 1 is considered to be the most severe ...

The condition is usually caused by mutations in a gene called SMN1, which contains instructions for how to make a protein called survival motor neuron (SMN) protein.This protein is critical for ...

But the voices represent a vast improvement on previous communication technologies and are already improving the lives of people with motor neuron diseases, says Richard Cave, a speech and ...

A new short film documenting the remarkable progress towards a treatment for Motor Neuron Disease (MND), also known as ALS, has been launched. A new short documentary showcasing the work into ...

Motor control refers to the process by which the nervous system coordinates the muscle and limbs to achieve a desired movement or set of actions. This includes the ability to anticipate, adjust ...

Motor neurons (MNs ... and increased innervation at the neuromuscular junction after 7 days, and it prolonged the mouse survival (Tsai et al., 2014). Importantly, this approach increased survival of ...

The neuromuscular junction (NMJ) is a synapse between motoneurons and skeletal muscles to control motor behavior. Unlike extensively investigated postsynaptic differentiation, less is known about ...

Now, Choi et al. have shown that amyloid precursor protein and LRP4 interact at the developing neuromuscular junction. A protein called agrin, which is produced by motor neurons and which must bind to ...