Naloxone is a fantastic tool in reducing opioid deaths, but gentler versions would be helpful for fighting overdose ...

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.

Below, check out the roundup of California Healthline's coverage. For today's national health news, read KFF Health News' Morning Briefing.

The mechanism of action of amyl nitrite and sodium ... μ-agonist whose toxic effects cannot be easily reversed with naloxone. Buprenorphine has a very high affinity for the μ-receptor and ...

The FDA has approved Journavx, a pain medication, offering a safer alternative to opioids. Learn about its benefits and side ...

Kratom has been used for hundreds of years in Southeast Asia for issues like fatigue. But it's banned in at least 6 states.

“It's the same mechanism by which you become addicted ... This is how people die of opioid overdoses and why Narcan, or naloxone, works to quickly block opioid receptors in the brain in order ...

Unlike opioids, which carry a high potential for misuse and dependency, suzetrigine works through a different mechanism and does ... and expanded access to naloxone, a life-saving overdose ...