Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland Doctoral School of Exact and Natural Sciences, Jagiellonian University, Prof. S. Łojasiewicza 11, 30-348 Kraków, ...
MTX acts as a folate antagonist and interrupts the synthesis of purines and pyrimidines, as well as the remethylation of homocysteine to form methionine, and multiple methyltransferase enzymes.