A transient ischemic attack (TIA), also called a mini-stroke, is a temporary loss of normal neurological function caused by a brief interruption of blood flow to part of the brain. The symptoms of a ...

An acute stroke, like most forms of stroke, starts suddenly and worsens rapidly. Some strokes may be preceded by a transient ischemic attack (TIA), a temporary stroke that resolves before causing any ...

Injury (trauma or ischemia) in the brain triggers an abnormal release of glutamate and other excitatory aminoacids that contribute significantly to neuronal death [1,2]. This phenomenon, named ...

Transplantation of neural stem cells improved neurologic and motor function for adults with chronic ischemic stroke at 12 months, according to a study presented at the International Stroke Conference.

These sleep loss changes are recovered by sleep. Sleep genes are enriched for synaptic shaping cellular components controlling glutamate synapse phenotype, overlap with autism risk genes, and are ...

State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China ...

Cerebral ischemic events disrupt the balance in uptake and re-synthesis, altering Glu, GABA, and glutamine (Gln) levels. We focused on the determining of the ratios of glutamate, GABA and glutamine in ...

The main cause of ischemic neuronal death is glutamate excitotoxicity. There have been multiple studies focusing on neuroprotection via reduction of glutamate both in ischemic stroke and other ...

Glutamate, the principal excitatory amino acid neurotransmitter in the CNS, is released at high levels after brain injury including cerebral ischemia. This leads to astrocyte swelling, which we ...

During cerebral ischemia, elevation of TNF-α and glutamate to pathophysiological levels may induce dysregulation of normal synaptic processes, leading ultimately to cell death. Previous studies ...