A chi-square test was performed to compare ALS patients with CG regarding commonly used MRI markers, including atrophy of the corpus callosum and spinal cord, as well as T2 hyper- and hypointensities ...

To visualize these structures, researchers use tractography, an imaging technique that calculates the course of nerve pathways based on specialized MRI scans. This information is particularly ...

hsr.it Objective To characterise in vivo the microstructural abnormalities of multiple sclerosis (MS) normal-appearing (NA) cortex and cortical lesions (CLs ... underwent a brain 3T MRI. Brain cortex ...

Inflammation plays an important role in the development of ALS, and associated with rapid disease progression. Current observational studies indicate the thinning of cortical thickness in patients ...

Next, we tested for associations between the measured MRI axonal diameter proxy and the disease duration. The rationale is that axonal swelling could be an early event in the disease, as suggested by ...

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of motoneurons in the primary motor cortex (pMO) and in spinal cord. However, the pathogenic process involves ...