Racial disparities in mortality are increasing. This article explores how the production of DNA-edited ethnically diverse ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

A new Yale study provides a fuller picture of the genetic changes that shaped the evolution of the human brain, and how the ...

A University of Ottawa neuroscientist has led a Canadian research team to reveal important new insights into the activation ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

With the addition of Casgevy, Children’s Hospital Los Angeles now offers two gene therapies for sickle cell, the first being Lyfgenia.

Treatment for sickle cell disease, the most common inherited blood disorder in Kenya, has been approved for use in England for older children and adults with a severe form of the disease.The treatment ...

Stem cell engineering and CRISPR were used to create mice with two male parents. Could we use this technique on humans?

Exagamglogene autotemcel (exa-cel) gene therapy offers a potential cure for severe sickle cell disease, now available on NHS.

Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice. The novel drug CT-179 was ...