A new review in Engineering reveals that CRISPR technologies are revolutionizing regenerative medicine. Scientists from ...

Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Since the mid-2010s, when biotech companies first began commercializing CRISPR-Cas9, historic milestones after ... Waving his cursor over a diagram in his PowerPoint presentation, Reed attempted to ...

using adeno-associated virus with transposon-based delivery of the CRISPR guide RNAs. Domain expansion contributes to diversification of RNA-guided endonucleases including Cas9. Here, authors ...

In addition, first-generation CRISPR systems (Cas9 and Cas12a) are too large for efficient in vivo delivery via a single adeno-associated viral (AAV) vector. Now, new preclinical research ...