Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

By contrast, adaptive immunity, which involves lymphocyte-like cells and the antigen-binding receptors ... During variable, diversity and joining region (V(D)J) recombination, the recombination ...

Once a peptide has been identified that binds with high affinity and specificity to an antibody antigen binding fragment (Fab), crystal structures ... spanning the 39 amino acid region with overlaps ...

in camelids sparked the most recent wave of “third generation” antibodies. Compared to conventional mAbs, HcAbs consist of just two heavy chains, with a single variable domain (VHH, ~15kDa) as the ...

Methods: Two different strategies of antibody humanization are popularly employed, including “complementarity determining region (CDR ... of key residues were performed to retain the antigen-binding ...

A review of recent trends and remaining challenges in bispecific antibody (bsAb) production has been published.

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

In this webinar, Daryl Cole will share insights into the high-throughput screening and analysis of antibody binding and functional characterization.

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Antibody-based therapeutics play a vital role in treating a wide range of diseases, but their manufacture can be complex, requiring efficient purification strategies to support product quality and ...