No writing assistance was utilized in the production of this manuscript. Future Oncol. 2009;5(3):339-357. © 2009 Future Medicine Ltd. Cite this: Oncolytic Adenoviral ...

CG Oncology's stock has dropped 40% since its IPO peak, driven by profit-taking and competitive concerns despite promising ...

Because adenovirus infections are fairly common ... Roctavian is also not cheap and costs nearly $2 million. Whether the gene-therapy product tested in the India will be affordable remains to ...

AB-207 is under clinical development by Angiocrine Bioscience and currently in Phase I for Anal Fissure. According to GlobalData, Phase I drugs for Anal Fissure does not have sufficient historical ...

As opposed to the US-FDA approved commercial gene therapy, Roctavian which uses an adenoviral vector, the CMC trial used a lentiviral vector with stem cell incorporation. This method is regarded ...

Ark's 'study 904', which was approved by the UK Gene Therapy Advisory Committee in ... virus gene for thymidine kinase (TK) encased in an adenoviral vector in which the E1 and part of the E3 ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

The company will use the proceeds to test its gene therapy XC001 in two Phase II studies involving patients with cardiovascular disease.

Ferring Pharma’s Adstiladrin is a non-replicating (cannot multiply in human cells) adenoviral vector-based gene therapy. Its safety and efficacy was evaluated in a multi-centre clinical study of ...

One recently approved gene therapy, CASGEVY TM (exagamglogene autotemcel), uses ... Traditionally this was done using viruses, such as adenovirus or lentivirus. While these can be effective tools, ...

for development of adenovirus-based gene therapies. That same year Novartis also formed a strategic alliance with GlaxoSmithKline and the Telethon Institute of Gene Therapy (TIGET) to pursue ...

NG-350A is an intravenously delivered, transgene-armed tumor gene therapy designed to drive ... chimeric group B adenovirus backbone which has been adapted via directed evolution to home ...