Promising Liver Cancer Therapies such as Atezolizumab, Bevacizumab, Tiragolumab, OH2 injection, MTL-CEBPA, Sorafenib 200mg, ...

Most mutations that decreased antibiotic susceptibility were related to specific metabolic pathways. A MIC-increase to ...

A biochemical reaction is the transformation of one molecule to a different molecule ... calcium signaling in neurons and cardiomyocytes, and adenosine triphosphate synthesis.

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...

A photopharmaceutical drug to treat psoriasis and avoid adverse effects The UB team has characterized the new compound MRS7787, a light-activatable molecule that binds to the A3 adenosine receptor ...

Design By utilising large scale transcriptome sequencing of three paired HCC clinical specimens and their adjacent non-tumour (NT) tissue counterparts at depth, we discovered an average of 20 007 ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...

This inhibition effectively disrupts the biochemical pathway responsible for the accumulation of adenosine, a molecule that can suppress the immune response. In contrast, Pz-039 is a targeted small ...

An artificial intelligence model has created a new protein that researchers say would have taken 500 million years to evolve in nature — if nature were capable of producing such a thing.

The US Patent Office has accepted patent application No 17/309,952, titled “An A3 adenosine receptor ligand for use for achieving a fat loss effect,” which is supported by the data showing Namodenoson ...

School of Pharmaceutical Sciences, University of Geneva, 1206 Geneva, Switzerland Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1206 Geneva, Switzerland School of ...

With the recent surge in popularity of weight loss drugs like Ozempic, altogether called GLP-1s, there has been renewed scientific interest in understanding how our bodies regulate muscle growth.