Given that alcohol is the most frequent functional group found in bioactive natural products and marketed drugs, and is a ...

Adding fluorine to drug molecules can be tricky, but is often worthwhile. Rachel Brazil talks to the chemists trying to tame ...

Chemical modification describes the modification, addition or removal, through chemical reaction, of any of a variety of macromolecules, including proteins and nucleic acids. It refers to the use ...

In particular, we study palladium-catalyzed allylic-addition reactions and explore the functioning of chiral ligands. We are most interested in how three-dimensional “chiral information” is ...