Naloxone, the opioid overdose antidote, is a powerful tool in the overdose crisis, allowing friends, loved ones and even bystanders a way to put a fatal overdose in reverse and bring back breathing.

A literature search identified more than a dozen published reports on the use of pure opioid antagonists (naloxone, naltrexone, methylnaltrexone) for the management of OIP in pediatric and adult ...

Aims: The use of medication in pain management currently involves empirical adjustment based on observed clinical outcome and the presence of adverse drug reactions. In this study ...