IN the course of chronic liver disease the development of portal hypertension and the ... shown to be caused by congenital intrahepatic portal–systemic shunts. N.F. (C–P.M.C. 151–33 ...

Although much research on the mechanisms of portal hypertension has focused on liver fibrosis, less attention has been given to the role of intrahepatic ... leading to increased portal vein pressure.

The therapeutic principle of portosystemic shunting is to convert the portal vein into an ... can be placed in the intrahepatic IVC, followed by a surgical infrahepatic shunt.

Hepatic vein thrombosis is caused by one ... Percutaneous angioplasty, followed by portosystemic shunt (including a transjugular intrahepatic portosystemic stent shunt) and eventually liver ...

"We are honored to receive Orphan Drug Designation for PLT012, a milestone that reflects our dedication to addressing the urgent need for innovative therapies in liver and intrahepatic bile ... to ...

With the recent development of venous-shunt surgery for the relief of portal hypertension a relatively ... on 100 patients with cirrhosis and intrahepatic portal-bed block, and 36 operations ...

Although BP-lowering treatment reduces the hypertension-related burden of disease, BP control continues to be poorly achieved worldwide. A major factor contributing to this therapeutic failure is ...