Abstract: The Two-Stage General Variable Neighborhood Search Algorithm (TSGVNS) proposed in this paper is a metaheuristic to solve the mixed integer nonlinear programming problem known as the Static ...

Jack Andrews, MD; Eugene Cone, MD; and Akshay Sood, MD, discuss how real-world safety and efficacy data for androgen receptor inhibitors (apalutamide, darolutamide, and enzalutamide) in nonmetastatic ...