Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

Some of them are brand new, others have been online for a while. Fans of British comedy troupe Monty Python will appreciate Tesla's latest hidden 'Easter egg' feature, which appears to pay tribute ...

Storms end Friday evening Wildfire smoke into Saturday Very warm early next week PLANNING THE NEXT 24 HOURS: Any storms, mainly Madison and areas east, will end tonight. Wildfire smoke from ...

PLANNING THE NEXT 24 HOURS: Conditions will be nice today with highs in the middle 70s along with mostly sunny skies. However, we still may see some lingering wildfire smoke, especially early ...

As crypto markets signal a potential trend reversal in early May, major Layer 1s like Solana (SOL), Ethereum (ETH), and XRP are flashing key signs of accumulation — a technical signal that has ...

Your blueprint for better Python architecture. pattern_kit is a developer-friendly Python library offering clean, idiomatic implementations of common software design patterns. It focuses on real-world ...