This vast chemical and structural space has created significant challenges for rational design of new structures and functions as the underlying molecular scale driving forces that give rise to ...

An integrated native mass spectrometry and top-down proteomics method that connects sequence to structure and function of macromolecular complexes. Nature Chem 10 , 139–148 (2018). https://doi ...

Improving the ability to predict protein function can potentially facilitate research in the fields of drug discovery and precision medicine. Technically, the properties of proteins are directly or ...