Ischemia and reperfusion are relevant to many disease states ranging from the impact of diabetes on the retina to stroke, cardiovascular disease and kidney dysfunction. 1,2 However, the current ...

They are studying a disease model called ischemia reperfusion injury, in which blood flow is removed then restored, inducing destructive inflammation, oxidative stress and resulting damage to ...

The study was the first to look at the role of arginase 1 in ischemic retinopathy using a common model called ischemia reperfusion injury, in which blood flow is removed then restored, which, like ...

CORK, Ireland, Sept. 26, 2017 /PRNewswire/ -- Ischemia-reperfusion (IR) injury, occurs in the body when blood supply returns to tissues after a period of oxygen and nutrient deprivation. It is an ...

Using retinal ischemia-reperfusion injury (RIRI) and primed mycobacterial uveitis (PMU) models, the researchers detected therapeutic benefits from the application of two different ExoCap ...

For the in vivo experiments, an ischemia-reperfusion model was created by subjecting mice to simulated HIRI. Ferroptosis occurrence, GPX4 promoter methylation, and global methylation levels were ...