Frontiers5d
Integrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer
Protein was extracted and estimated using BCA (Bicinchoninic Acid) protein assay (Pierce, ThermoFisher Scientific). Reduction, alkylation, and precipitation of an equal amount of protein from each ...
BMJ6d
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
Objectives Metabolic changes are crucially involved in osteoclast development and may contribute to bone degradation in rheumatoid arthritis (RA). The enzyme aconitate decarboxylase 1 (Acod1) is known ...