Bits of viral genes incorporated into human DNA have been linked to cancer, ALS and schizophrenia. But many of these genes ...

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

The MDU will accept requests for sequencing of virus or provirus in samples other than plasma, such as lymphocytes, and cerebrospinal fluid (CSF). The routine test for resistance to protease and ...

Longitudinal analysis of the change in (C) intact and (D) defective provirus copies in the 6 months after ART initiation, comparing the acute treated (blue) and chronic treated (green) groups. Dots ...

Both intact and total proviral DNA levels showed a positive correlation with T cell activation and exhaustion, whereas ART duration and HIV-specific CD4 T cell responses were negatively correlated ...

We know today that Wnt and a handful of other signalling systems (Notch, Hedgehog, TGFβ (transforming growth factor-β)–BMP (bone morphogenetic protein) and receptor tyrosine kinases) are major ...

HIV invasion through the mucosa of the female lower genital tract contributes the largest number of new HIV infections worldwide. The second leading site of viral invasion is the lower male ...

Background: The use of highly active antiretroviral therapy has transformed AIDS into a chronic infectious disease, but issues of chronic inflammation and immune system activation persist. Modulating ...

1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...