Enzyme kinetic data from the BRENDA database were mapped onto the genome-scale metabolic model of Saccharomyces cerevisiae to ...

Increasing the ERK pathway activity prolonged ketamine’s effectiveness in mouse models of depression. This paper shows that targeting the downstream effects that ketamine causes in the brain can ...

“We believe PAS-004’s profile offers the potential to finely modulate MAPK pathway activity, enabled by its previously reported long half-life and favorable pharmacokinetic (PK) profile with a ...

(A, C, and E), Before and (B, D, F) after. To investigate the activity of RAF1 S259P mutant, we performed western blot. Constitutively, active RAF1 S257 mutant was used as a positive control. RAF1 ...

Methylene blue is rapidly gaining ground as a leading cognitive enhancement supplement, renowned for its role in bolstering mitochondrial health, energy production, and mental clarity. As consumer ...

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections ...

What’s more, some forms of reishi may alter inflammation pathways in white blood cells ... traditional treatment by increasing the activity of white blood cells and improving quality of life.

In most patient tumors, resistant cancer cells increased ERBB growth pathway activity during treatment, only partially through ERBB receptor upregulation. Concurrently, fibroblasts within the tumor ...