Protein 'seeds' trigger key pathological features of ALS and frontotemporal dementia
Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a study published in Neuron, ...
Technology Networks17h
New Model Mimics TDP-43 Aggregation in ALS and Frontotemporal Dementia
Researchers have developed a laboratory model that mimics the pathological aggregation of TDP-43, a key protein in ALS and ...
Uncovering the relationship between transport proteins and brain disease
Most of us rely heavily on shipping services like FedEx or UPS to ensure we receive the correct packages. If that system was ...
Ansa on MSN1h
Court denies 'assisted suicide' to woman with ALS
A court in Trieste has rejected a request filed by Martina Oppelli, who has had the fatal nerve-wasting disease Amyotrophic ...
Technology Networks2d
Kinase Inhibitors: Promising Therapeutics for Neurodegenerative Diseases
This article introduces the role of kinases in neurodegenerative diseases, the development of kinase inhibitors for the ...
Mitsubishi Tanabe Pharma America Announces Publication of Preclinical Research on the Role of Edaravone in Mitigating TDP-43 Mislocalization in ALS
Mitsubishi Tanabe Pharma America, Inc. (MTPA) today announced the publication of new preclinical research in Free Radical Biology and Medicine, highlighting the role of edaravone in mitigating TDP-43 ...
University at Buffalo4d
Empire AI projects showcase UB’s commitment to harnessing AI for the public good
With Empire AI, UB is helping people with ALS, improving medical imaging, boosting mental health resources and much more.
Le Lézard3d
ALZpath Adds Biotech Veteran to Board of Directors and Names Prominent Global Researcher as Distinguished Scientific Advisor
ALZpath, Inc. (ALZpath), a leading developer of diagnostic tools and solutions for Alzheimer's disease and related dementias, announced the addition of Samantha Budd Haeberlein, PhD, to its board ...
ALZFORUM1d
Filling in the Family Tree—AD, CTE Folds Spotted in Other Tauopathies
Dysfunctional Family. A family tree of tau folds now incorporates two new structures—P301L, P301T (bottom)—and fills in ...
Ansa on MSN4d
Judge orders end-of-life activists' forced indictment
A preliminary investigations judge (GIP) in Florence on Monday rejected a request filed by the State Attorney's office to ...
ALS News Today1d
Study highlights role of natural killer immune cell subsets in ALS
Certain subsets of immune NK cells were altered in the blood of people with ALS, and could serve as therapeutic targets, a ...