A breakthrough study has uncovered a hidden player in Parkinson’s disease—24-OHC, a cholesterol metabolite that fuels the ...

A comprehensive analysis has identified novel enhancers associated with neuronal development and disease.

Researchers’ understanding of the pathogenesis of rheumatoid arthritis has grown considerably in recent years, laying the ...

Researchers at Shanghai Huashan Hospital have identified a novel therapeutic target that could lead to the world's first ...

At the Rutgers American Parkinson Disease Association Center for Advanced Research —one of only nine such centers—we don’t just seek to treat the symptoms of Parkinson’s but to cure it. By focusing on ...

IntroductionOxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role in the ...

John Sacaria Thirusailam, once very active in life, was forced to leave his well-paid job at the age of 44 after being ...

Researchers suggest drugs that prevent cholesterol from being converted to 24-OHC might therefore be an effective treatment for Parkinson's disease.

A photothermal, nanoparticle-based deep brain stimulation system restored motor skills in mice with Parkinson’s-like disease ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...