Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role ...

A breakthrough study has uncovered a hidden player in Parkinson’s disease—24-OHC, a cholesterol metabolite that fuels the ...

A comprehensive analysis has identified novel enhancers associated with neuronal development and disease.

Researchers’ understanding of the pathogenesis of rheumatoid arthritis has grown considerably in recent years, laying the ...

Parkinson’s disease and Lewy Body Dementia (LBD) are two serious brain conditions that affect millions of people in the U.S.

Researchers at Shanghai Huashan Hospital have identified a novel therapeutic target that could lead to the world's first ...

At the Rutgers American Parkinson Disease Association Center for Advanced Research —one of only nine such centers—we don’t just seek to treat the symptoms of Parkinson’s but to cure it. By focusing on ...

IntroductionOxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role in the ...

John Sacaria Thirusailam, once very active in life, was forced to leave his well-paid job at the age of 44 after being ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease ...