A comprehensive analysis has identified novel enhancers associated with neuronal development and disease.

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...

Kazia Therapeutics (KZIA) announced a research grant awarded from The Michael J. Fox Foundation for Parkinson’s Research, MJFF, to fund ...

IntroductionOxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role in the ...

Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Down Syndrome, are increasingly being linked to cellular ...

Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role ...

Researchers suggest drugs that prevent cholesterol from being converted to 24-OHC might therefore be an effective treatment for Parkinson's disease.

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.

The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Free radicals are produced in the body during normal cellular metabolic activities, and their excessive accumulation can overwhelm the natural antioxidant mechanisms. This leads to oxidative stress, ...