This article discusses the roles of neutrophils and G-CSF during chronic inflammatory diseases. In addition to causing direct tissue damage, activated neutrophils can modulate inflammation via the ...

Chronic obstructive pulmonary disease (COPD) is a complex disease in which neutrophils play a central ... However, many other pro- and anti-inflammatory mediators are also altered in COPD which ...

Neutrophil granulocytes, a type of immune cell, are indispensable for the defense against pathogens. However, if they migrate ...

Neutrophil granulocytes, a type of immune cell, are indispensable for the defense against pathogens. However, if they migrate into injured tissue, for example into the brain after a stroke, they can ...

The researchers also demonstrated that scratching prompts pain-sensing neurons to release a chemical known as substance P, which triggers mast cells: cells involved in the immune system, causing ...

However, on infiltrating the sAH liver, these neutrophils are stimulated by the inflammatory environment, including mediators such as TNF-α and IL-1β, to produce high levels of IL-8. This IL-8 ...