Researchers have shown previously that excessive proliferation of the cells of the brain, which can cause macrocephaly, or large head size, is associated with autism. Now, the authors of a study ...

PTEN gene sequencing should be considered in any child with macrocephaly and autism or developmental delay. Metabolic screening may not be warranted in autism spectrum disorders without more ...

The researchers predicted that the new tool will enable the development of personalized therapeutics by monitoring PTEN ...

There is growing evidence that mutations in PTEN, which reduce its activity, contribute to diseases like autism, macrocephaly, cancer, and epilepsy. "Despite the critical role PTEN plays in ...