Esperion Therapeutics has two approved LDL-C lowering therapies, Nexletol and Nexlizet, but lacks a strong pipeline for future growth.

Tamarind, a tropical fruit rich in nutrients and fiber, is gaining attention for its potential to aid in weight loss, ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Engineered enzymes are poised to have transformative impacts across applications in energy, materials, biotechnology, and medicine. Recently, machine learning has emerged as a useful tool for ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...

To address this, all experiments were conducted in a sterile environment to exclude the effects of enzyme contamination. All reaction components were solubilized in nuclease-free water. Moreover, the ...

Rubisco is the enzyme responsible for carbon fixation in plants, algae and many bacteria. A screen of a comprehensive library of rubisco variants (each with a different single-amino-acid mutation ...

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...

In this study, we screened the high-producing alginate lyase Vibrio xiamenensis QY104. The fermentation broth was purified to obtain the native enzyme VxAly7B. Temperature and time were the main ...