To further understanding of QbD concepts to analytical method development and validation, the tools suggested in the Stimuli article were combined with the guidance in ICH Q2(R1) (5) ... Potential ...

When you encounter a problem, the most effective method of solving it is by getting to the root cause. You can create a fishbone diagram to help yourself determine that.

A fishbone diagram can be a great tool to help improve analytical skills. It encourages critical and systematic thinking about a problem and its causes, while providing a visual and structured way ...

The diagram looks like a fishbone, with the head representing the problem or the effect, and the bones representing the main categories of causes. Each category can have subcategories and more ...

Focusing on separating small molecule samples by liquid chromatography, “A Practical Guide to Analytical Method Development” will study all steps for a manual approach to this process, guided ...

To further understanding of QbD concepts to analytical method development and validation, the tools suggested in the Stimuli article were combined with the guidance in ... Instrument malfunction was ...