New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses ...

Most cases are caused by mutations in the genes encoding for the subunits composing type V collagen, an essential component of the extracellular matrix in many of the connective tissues in the body.

Of course, external signals from neighboring cells or from the extracellular matrix are also important influences on the arrangement of cells in a tissue. Without cell division, long-term tissue ...

Matrix elements and fibrotic changes. Major components of the extracellular matrix (connective tissue) of the liver and the four most important changes in the fibrotic matrix. Formal pathogenesis ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

Tendons have the highest tensile strength of all connective tissue because of a high proportion ... as tenocytes synthesise both fibrillar and non-fibrillar components of the extracellular matrix, and ...

The study highlights the extracellular matrix protein 1 ... characterized by the "scarring" of the liver as liver tissue is replaced by connective tissue, leading to a progressive loss of liver ...

J Gastroenterol Hepatol. 2008;23(7):1024-1035. Cite this: Changing the Pathogenetic Roadmap of Liver Fibrosis? Where Did It Start; Where Will It Go? - Medscape - Jul 01, 2008. 1869 F. Boll Star ...