The “classical” pathway of the complement system is triggered when C1q binds to antibodies that are already bound to antigens on a cell surface. It only comes into effect when a high number of ...

A collaborative team from Penn Medicine and Penn Engineering has uncovered the mathematical principles behind a ...

Functional and mechanistic analyses demonstrated that TSP-1 regulates complement activation by binding multiple central alternative complement pathway components, thereby attenuating the cascade ...

A collaborative team from the School of Engineering and Applied Science and the Perelman School of Medicine have unraveled the mathematics of a 500-million-year-old protein network that acts like the ...

Fans -- and we shall use this term for lack of a better one -- could buy up to six cups at a time, with no system in place to prevent a designated mule from purchasing a full complement ...

Purpose: To evaluate whether low CH50 (a comprehensive measure of hemolytic activity of the classical complement pathway) is associated with infection-related coagulopathy, organ dysfunction, and poor ...

Crystal precipitation from aqueous solution occurs through multiple pathways. Besides the classical ion -byion addition, non-classical crystallization mechanisms, such as multi-ion polymer and ...

Asthma nurses introduced an ongoing system to educate medical and nursing staff rotating through ED and the medical wards regarding the Care Pathway. Initially there was a problem with both under and ...

The following criteria were used to match the identification method: ISE between the response of the real system and the model and the normalized delay time. The work used two different tuning ...

Our understanding of the cellular and molecular mechanisms of chemosensation in the trigeminal system has experienced enormous progress in the past decade, following the cloning and functional ...