The quest to resurrect the woolly mammoth on Earth has taken another, well, small step with the creation of the Colossal ...

The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about genetic safety and efficacy.

The same study [13] showed that L1TD1 localizes to high-density RNP condensates and enhances the translation ... deletion in the exon 4 of the DNMT1 gene were generated using CRISPR/Cas9 gene editing.

RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient, convenient and programmable, leading to promising ...

Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22904, United States Carter Immunology Center and University of Virginia Cancer Center, University of Virginia ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Control of gene expression is commonly ...