In this webinar, Daryl Cole will share insights into the high-throughput screening and analysis of antibody binding and functional characterization.

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

A new experimental vaccine developed by researchers at MIT and Caltech could offer protection against emerging variants of SARS-CoV-2, as well as related coronaviruses, known as sarbecoviruses, that ...

Once a peptide has been identified that binds with high affinity and specificity to an antibody antigen binding fragment (Fab), crystal structures ... spanning the 39 amino acid region with overlaps ...

While there are only five main types of antibodies, each can have a different binding site that matches a specific antigen. Your body can produce an infinite number of binding sites to bind to ...

Antibody-based therapeutics play a vital role in treating a wide range of diseases, but their manufacture can be complex, requiring efficient purification strategies to support product quality and ...

(2) These cells are activated using anti-CD3/CD28 antibodies to stimulate their proliferation ... a follow-up experiment showed that the PD-1–blocking scFv secreted by antigen-irrelevant CAR-T cells ...

in the absence of stabilizing antibodies or mutations. The substrate-binding site is located within one half of the molecule and, in the apo state, is obstructed by the transmembrane helix (TM) 4.

Naked mAbs are antibodies that have no drug or radioactive material attached to them. They work by themselves. These are the most common type of mAbs used to treat cancer. Most naked mAbs attach to ...

Omalizumab mechanism of action. Omalizumab binds to the Ce3 domain of immunoglobulin E (lgE) and prevents free lgE from binding to the mast cell FceRI receptor. Data courtesy of Genentech ...