The variable region confers an antibody's antigen-binding specificity. This region contains two fragment antigen binding (Fab) domains, each capable of binding a specific epitope (the part of an ...

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

A full-size IgG antibody is a Y-shaped complex of two identical light chains, each with a variable and constant ... The percentage of fragments that bind tumor cell antigens was 48% and 35% ...

A review of recent trends and remaining challenges in bispecific antibody (bsAb) production has been published.

By cloning the variable regions of the heavy and light chains of antibodies from immunized blood donors together on a single coding region, the two produced a fusion protein with all of the antigen ...

One of the most utilized tools in biomedical research is the monoclonal antibody. These proteins have the potential to seek out and bind to any ... of the target antigen. Here are two case studies ...