As our virtual heart tour continues, we gather around a bisected heart, watching valves open and close. The teacher prompts us to trace the blood flow — “oxygenated or deoxygenated?” he asks.

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

Introduction The past decade has witnessed significant advancements in genome-targeted oncology drugs within the realm of precision medicine (PM). However, the cost-effectiveness of oncology PM in a ...

Conventional vehicle suspension systems, often relying on integer-order models with fixed damping coefficients, struggle to deliver optimal performance across diverse an ...

Main text – usually no longer than 2,200 words, but can be up to 3,000 words at the editor’s discretion (excluding abstract, Methods, references and figure legends).