Within the ribosome, the mRNA and aminoacyl-tRNA complexes are held together closely, which facilitates base-pairing. The rRNA catalyzes the attachment of each new amino acid to the growing chain.

For each, they determined whether the aminoacyl-tRNA was bound to the short mRNA-like sequence and ribosome (the rest passed through the filter), providing conclusive demonstrations of the ...

We are using this technology for: 1) The development of new bioorthogonal conjugation reactions, especially ones that are ... In order to facilitate these applications, we have: 1) Developed new ...

Defects in tRNA biology, such as mutations in tRNA genes or aminoacyl-tRNA synthetases, can lead to various diseases, including: Understanding the mechanisms of tRNA-related diseases and the potential ...