Serotonin syndrome is a preventable, drug-related complication that results from increased brain-stem serotonin activity, usually precipitated by the use of one or more serotonergic drugs.

See Contraindications. Do not give with citalopram. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium ...