There are still less effective neuroprotective strategies in ischemic stroke due, in part, to gaps between preclinical and clinical studies, such as model differences and the difficulty in effectively ...

Author response: The following is the authors’ response to the original reviews. eLife assessment: The manuscript establishes a sophisticated mouse model for acute retinal artery occlusion (RAO) by ...

Given the similarities between these two types of neuronal injury, we conducted a parallel study of the EPO/EPO-R system in a model of retinal ischemia-reperfusion injury. EPO is expressed in the ...

Keywords: ischemia/reperfusion, ERG, retinal thickness, retinal ganglion cell, timeline, photoreceptor, amacrine cell, bipolar cell Citation: Palmhof M, Frank V, Rappard P, Kortenhorn E, Demuth J, ...

Hartsock, M.J., et al. (2016) A Mouse Model of Retinal Ischemia-Reperfusion Injury through Elevation of Intraocular Pressure. Journal of Visualized Experiments, No. 113. has been cited by the ...

Establishment of the Retinal Ischemia/Reperfusion (I/R) Model. Rats were anesthetized with an intraperitoneal (i.p.) injection of xylazine (10 mg/kg) and ketamine (100 mg/kg). 1% tropicamide was then ...

Ischemia and reperfusion are relevant to many disease states ranging from the impact of diabetes on the retina to stroke, cardiovascular disease and kidney dysfunction. 1,2 However, the current ...

There are still less effective neuroprotective strategies in ischemic stroke due, in part, to gaps between preclinical and clinical studies, such as model differences and the difficulty in effectively ...

Furthermore, the authors compared transcriptomic differences between the UPOAO model and other retinal ischemic-reperfusion models, including HIOP and UCCAO, and revealed unique pathological processes ...