The F and G proteins are the only viral components that induce neutralizing antibodies and are the primary targets of the humoral response. RSV is a major seasonal viral respiratory pathogen in ...

Zhu and his research team first analyzed the F proteins used in the development of four existing RSV vaccines—the commercially available Arexvy, mResvia and Abrysvo, and an experimental vaccine ...

The trimeric pre-fusion glycoprotein F is essential for accurately assessing the immunogenicity of RSV vaccines. We strictly adhere to ... whether it comes through recombinant proteins, antibodies, ...

First, they must enter the host cells, which RSV does using its fusion (F) protein. Vaccines induce antibodies that bind to pathogens. Neutralizing antibodies bind to crucial sites, such as part ...

The two vaccines induce the immune system to target a critical protein on the surface of RSV, the F protein, in its pre-infection form, known as pre-fusion F. High levels of antibodies against pre ...

BLB201 encodes the RSV F protein and uses a proprietary PIV5 vector, which is not known to cause human disease. PIV5 has been commonly administered to dogs as part of combination distemper/kennel ...

Here, we describe the epidemiology of RSV, the RSV virion structure ... the small hydrophobic protein, the glyco (G) attachment protein and the fusion (F) protein. The F and G proteins are ...