A single base change can create a devastating genetic disorder or a beneficial adaptation, or it might have ... sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a ...

This is sickle cell anemia. But it takes two copies of the mutant gene, one from each parent, to give someone the full-blown disease. Many people have just one copy, the other being normal.

Understanding the influence that sickle cell disease and economic deprivation have on brain structure may lead to treatments ... the study – calculated each person’s brain age using a brain ...

Sickle cell disease (SCD) has been historically overlooked and underfunded. For years, people living with SCD ... difficulties that many patients may face in pursuing innovative treatment options.

Now a multidisciplinary team of researchers and physicians at Washington University School of Medicine in St. Louis has published a study that helps explain how the illness might affect cognitive ...