Two enzymes, a peptidase and a cyclase, then collaborate to convert a linear precursor peptide into the distinctive knotted ...

I was a young enzymologist looking for a new project, and immediately volunteered for this one, which involved a peptidase of apparently unique mechanism and an enzyme product of potentially great ...

Signal peptidase (SPase) is the membrane bound serine ... This is another example of an enzyme with a serine/lysine catalytic dyad mechanism, but with no sequence or structural homology to SPase. For ...