All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

Other NSAIDs do not have this effect. Cox-2 inhibitors are a newer form of prescription NSAID. As you might guess, they only affect Cox-2 enzymes and not Cox-1. Two of them -- Bextra and Vioxx ...

Both are types of NSAIDs, but they work differently. Celebrex is a selective COX-2 inhibitor that targets inflammation with ...

That's because most NSAIDs, like ibuprofen, are COX-1 inhibitors, which block prostaglandins that produce inflammation. However, prostaglandins also protect your stomach lining (per the National ...

Inhibition of these activities is responsible for most of the side effects of NSAIDs. NSAID research changed radically with the discovery that COX existed in two isoforms: the constitutively ...

like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Famotidine is a competitive inhibitor of histamine H 2-receptors. The primary ...

Its mechanism of action for analgesia, like that of other NSAIDs, is not completely understood, but involves inhibition of cyclooxygenase (COX-1 and COX-2). Because ibuprofen is also an inhibitor ...

[21] However, the ranking of NSAIDs as inhibitors of COX and interpretation of rank orders to inform evidence of clinical toxicity has continued unabated. As would be anticipated with the ...